This paper is an attempt to check the impact of income inequality, population growth and trade liberalization on poverty in Pakistan. Human Development Index (HDI) is used as dependent variable and Gini coefficient, population growth rate, political stability (dummy variable) trade liberalization and lagged HDI as independent variables. The results suggest that income inequality and population growth has positive relation with poverty while trade liberalization has negative relation with poverty. If Pakistan wants to reduce poverty then there is a need to control population growth and income inequality gap. On the other hand there is a dire need for globalization and trade liberalization.